In 2017, Nithiin acted in the film LIE which was directed by Hanu Raghavapudi. It garnered average reviews from critics, but the song "Bombhaat" which was composed by Mani Sharma became famous. Despite this, the film could not do well at the box office and ended up as a double disaster.
In 2018, Nithiin's Chal Mohan Ranga directed by Krishna Chaitanya with co-star Megha Akash opened to average reviews from critics. It was criticised for the routine story from Trivikram but was praised for its comedy. The music composed by S. Thaman became very popular. However, this film also ended up as a disaster at the box office. On August 9, 2018, another film of Nithiin's titled Srinivasa Kalyanam released. It was directed by Satish Vegesna and his co-star was Raashi Khanna. It got average reviews from critics and was a "hat-trick disaster" for Nithiin, as Telugu360 stated